hrp0095p2-64 | Diabetes and Insulin | ESPE2022

Diabetes Secondary to Glucokinase Gene Polymorphism with Obesity and Fluctuating Severity of Diabetes

Aljalily Sarraa , Xu Xu , Ten Svetlana

Case report: 14 yrs. old Hispanic girl was referred for evaluation of diabetes (Hb A1c 9.8 %) and morbid obesity BMI 36 kg/m2. She developed acanthosis nigricans, elevated triglycerides (TG) 1162 mg/dl, low HDL 34 mg/dl, fatty liver with elevated AST 84 U/l, ALT 103 U/L. The abdominal sonogram revealed significant hepatomegaly with moderate steatosis. Her islet cell AB were negative, C-peptide 3.11 ng/ml was normal. She has a strong family history of diabetes:...

hrp0095p1-589 | Thyroid | ESPE2022

Familial Dysalbuminemic Hyperthyroxinemia (FDH) in Asymptomatic Child with High Free T4 and Normal TSH

Shanza Afzaal Shanza , Aljalily Sarraa , Malheiros - França Monica , Ten Svetlana

Case report: 6 yrs. old boy presented with high total T4, free T4, reverse T3, and normal total T3 and TSH. He has a history of tic disorder. Blood pressure, and heart rate were normal, no palpitations, no weight loss. Thyroid peroxidase and thyroglobulin antibodies were normal. Thyroid sonogram was normal. Family is of Hispanic origin. There was a family history of elevated T4 in the paternal uncle (half-brother of the father)Me...